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1

Camptothecin and taxol: from discovery to clinic

Monroe E. Wall, Mansukh C. Wani

Journal:

Journal of Ethnopharmacology

Year:

1996

Language:

english

File:

PDF, 1.20 MB

english, 1996

2

Complete isolation and characterization of silybins and isosilybins from milk thistle (Silybum marianum)Electronic supplementary information (ESI) available: HPLC chromatograms of isolates and extracts. See http://www.rsc.org/suppdata/ob/b3/b300099k/

Kim, Nam-Cheol, Graf, Tyler N., Sparacino, Charles M., Wani, Mansukh C., Wall, Monroe E.

Journal:

Organic & Biomolecular Chemistry

Year:

2003

Language:

english

File:

PDF, 157 KB

english, 2003

3

Design, Synthesis, and Biological Evaluation of Antibody−Drug Conjugates Comprised of Potent Camptothecin Analogues

Burke, Patrick J., Senter, Peter D., Meyer, David W., Miyamoto, Jamie B., Anderson, Martha, Toki, Brian E., Manikumar, Govindarajan, Wani, Mansukh C., Kroll, David J., Jeffrey, Scott C.

Journal:

Bioconjugate Chemistry

Year:

2009

Language:

english

File:

PDF, 677 KB

english, 2009

4

Camptothecin analogs with enhanced activity against human breast cancer cells. II. Impact of the tumor pH gradient

David J. Adams, Miriam L. Wahl, James L. Flowers, Banalata Sen, Michael Colvin, Mark W. Dewhirst, Govindarajan Manikumar, Mansukh C. Wani

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2006

Language:

english

File:

PDF, 330 KB

english, 2006

5

Novel Strategies for the Discovery of Plant-Derived Anticancer Agents

Kinghorn, A., Farnsworth, Norman, Soejarto, Djaja, Cordell, Geoffrey, Swanson, Steven, Pezzuto, John, Wani, Mansukh, Wall, Monroe, Oberlies, Nicholas, Kroll, David, Kramer, Robert, Rose, William, Vite

Journal:

Pharmaceutical Biology

Year:

2003

Language:

english

File:

PDF, 154 KB

english, 2003

6

Nature as a remarkable chemist

Wani, Mansukh C., Horwitz, Susan Band

Journal:

Anti-Cancer Drugs

Year:

2014

Language:

english

File:

PDF, 431 KB

english, 2014

7

Special Issue in Honor of Professor Susan Band Horwitz

Mooberry, Susan L., Kingston, David G. I., Smith, Amos B., Swanson, Steven M., Wani, Mansukh C.

Journal:

Journal of Natural Products

Year:

2018

Language:

english

File:

PDF, 1.02 MB

english, 2018

8

ChemInform Abstract: Cytotoxic Constituents from the Roots of Tovomita brevistaminea.

Eun-Kyoung Seo, Monroe E. Wall, Mansukh C. Wani, Hernan Navarro, Rabindranath Mukherjee, Norman R. Farnsworth, A. Douglas Kinghorn

Journal:

Year:

2000

File:

PDF, 27 KB

2000

9

Complete Isolation and Characterization of Silybins and Isosilybins from Milk Thistle (Silybum marianum).

Nam-Cheol Kim, Tyler N. Graf, Charles M. Sparacino, Mansukh C. Wani, Monroe E. Wall

Journal:

Year:

2003

File:

PDF, 85 KB

2003

10

The preparation of tritium and deuterium-labelled camptothecin

Peter E. Ronman, Mansukh C. Wani, Monroe E. Wall

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1981

Language:

english

File:

PDF, 348 KB

english, 1981

11

Synthesis of position-specific tritium-labeled 20(S)-camptothecin, 9-amino-20(S)-camptothecin, and 10,11-methylenedioxy-20(S)-camptothecin

Allan W. Nicholas, Mansukh C. Wani, Monroe E. Wall, John A. Kepler, George F. Taylor

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1993

Language:

english

File:

PDF, 474 KB

english, 1993

12

Two isoflavones from the bark of Petalostemon purpureus

Swapan K. Chaudhuri, Fekadu Fullas, Mansukh C. Wani, Monroe E. Wall, John C. Tucker, Christopher W.W. Beecher, A.Douglas Kinghorn

Journal:

Year:

1996

Language:

english

File:

PDF, 175 KB

english, 1996

13

Two isoflavones from the bark of Petalostemon purpureus

Swapan K. Chaudhuri, Fekadu Fullas, Mansukh C. Wani, Monroe E. Wall, John C. Tucker, Christopher W.W. Beecher, A.Douglas Kinghorn

Journal:

Year:

1996

Language:

english

File:

PDF, 184 KB

english, 1996

14

Novel A-ring modified camptothecins as topoisomerase I inhibitors

Michael R. Peel, Mark W. Milstead, Daniel D. Sternbach, Jeffrey M. Besterman, Peter Leitner, Bradley Morton, Monroe E. Wall, Mansukh C. Wani

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 188 KB

english, 1995

15

Palladium/hydrogen catalyzed alcoholysis of benzylsilanes

Colin G. Pitt, Alan E. Friedman, Douglas H. Rector, Mansukh C. Wani

Journal:

Journal of Organometallic Chemistry

Year:

1976

Language:

english

File:

PDF, 308 KB

english, 1976

16

New bioactive aromatic compounds from Vismia guianensis

Eun-Kyoung Seo, Mansukh C Wani, Monroe E Wall, Hernan Navarro, Rabindranath Mukherjee, Norman R Farnsworth, A.Douglas Kinghorn

Journal:

Year:

2000

Language:

english

File:

PDF, 215 KB

english, 2000

17

Triterpenes from the combined leaf and stem of Lithospermum caroliniense

Fekadu Fullas, Mansukh C. Wani, Monroe E. Wall, John C. Tucker, Christopher W.W. Beecher, A. Douglas Kinghorn

Journal:

Year:

1996

Language:

english

File:

PDF, 241 KB

english, 1996

18

Cytotoxic constituents from the roots of Tovomita brevistaminea

Eun-Kyoung Seo, Monroe E. Wall, Mansukh C. Wani, Hernan Navarro, Rabindranath Mukherjee, Norman R. Farnsworth, A.Douglas Kinghorn

Journal:

Year:

1999

Language:

english

File:

PDF, 145 KB

english, 1999

19

The activity of camptothecin analogues is enhanced in histocultures of human tumors and human tumor xenografts by modulation of extracellular pH

James L. Flowers, Robert M. Hoffman, Timothy A. Driscoll, Monroe E. Wall, Mansukh C. Wani, Govindarajan Manikumar, Henry S. Friedman, Mark Dewhirst, O. Michael Colvin, David J. Adams

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2003

Language:

english

File:

PDF, 284 KB

english, 2003

20

Camptothecin analogs with enhanced activity against human breast cancer cells. I. Correlation of potency with lipophilicity and persistence in the cleavage complex

David J. Adams, Mateus Webba da Silva, James L. Flowers, Glenda Kohlhagen, Yves Pommier, O. Michael. Colvin, Govindarajan Manikumar, Mansukh C. Wani

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2006

Language:

english

File:

PDF, 509 KB

english, 2006

21

Novel fluoro-substituted camptothecins: in

William C. Rose, Punit H. Marathe, Graham R. Jang, Thomas M. Monticello, Balu N. Balasubramanian, Byron Long, Craig R. Fairchild, Monroe E. Wall, Mansukh C. Wani

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2006

Language:

english

File:

PDF, 618 KB

english, 2006

22

BACPTDP: a water-soluble camptothecin pro-drug with enhanced activity in hypoxic/acidic tumors

David J. Adams, William R. Waud, Mansukh C. Wani, Govindarajan Manikumar, James L. Flowers, Timothy A. Driscoll, Lee Roy Morgan

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 556 KB

english, 2011

23

Camptothecin analogues with enhanced antitumor activity at acidic pH

David J. Adams, Mark W. Dewhirst, James L. Flowers, Michael P. Gamcsik, O. Michael Colvin, Govindarajan Manikumar, Mansukh C. Wani, Monroe E. Wall

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2000

Language:

english

File:

PDF, 176 KB

english, 2000

24

Plant antitumour agents-XV: Isolation and x-ray crystal structure of a new antileukaemic quassinoid undulatone from Hannoa undulata

Mansukh C. Wani, Harold L. Taylor, James B. Thompson, Monroe E. Wall, Andrew T. McPhail, Kay D. Onan

Journal:

Year:

1979

Language:

english

File:

PDF, 770 KB

english, 1979

25

Novel bioactive phenanthrene derivatives from Domohinea perrieri

Lina Long, Sang Kook Lee, Hee-Byung Chai, Philippe Rasoanaivo, Qi Gao, Hernán Navarro, Monroe E. Wall, Mansukh C. Wani, Norman R. Farnsworth, Geoffrey A. Cordell, John M. Pezzuto, A. Douglas Kinghorn

Journal:

Year:

1997

Language:

english

File:

PDF, 492 KB

english, 1997

26

Discovery to Clinic

MONROE E. WALL, MANSUKH C. WANI

Journal:

Annals of the New York Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 580 KB

english, 1996

27

Dereplication of macrocyclic trichothecenes from extracts of filamentous fungi through UV and NMR profiles

Sy-Cordero, Arlene A, Graf, Tyler N, Wani, Mansukh C, Kroll, David J, Pearce, Cedric J, Oberlies, Nicholas H

Journal:

The Journal of Antibiotics

Year:

2010

Language:

english

File:

PDF, 625 KB

english, 2010

28

Comparative molecular field analysis and molecular modeling studies of 20-(S)- camptothecin analogs as inhibitors of DNA topoisomerase I and anticancer/antitumor agents

Sean W. Carrigan, Peter C. Fox, Monroe E. Wall, Mansukh C. Wani, J. Phillip Bowen

Journal:

Journal of Computer-Aided Molecular Design

Year:

1997

Language:

english

File:

PDF, 117 KB

english, 1997

29

Plant Antimutagens, 6. Intricatin and Intricatinol, New Antimutagenic Homoisoflavonoids from Hoffmanosseggia intricata

Wall, Monroe E., Wani, Mansukh C., Manikumar, G., Taylor, Harold, McGivney, Robert

Journal:

Journal of Natural Products

Year:

1989

Language:

english

File:

PDF, 280 KB

english, 1989

30

Peptaibols from two unidentified fungi of the order Hypocreales with cytotoxic, antibiotic, and anthelmintic activities

Sloan Ayers, Brandie M. Ehrmann, Audrey F. Adcock, David J. Kroll, Esperanza J. Carcache de Blanco, Qi Shen, Steven M. Swanson, Joseph O. Falkinham III, Mansukh C. Wani, Sheila M. Mitchell, Cedric J.

Journal:

Journal of Peptide Science

Year:

2012

Language:

english

File:

PDF, 1.84 MB

english, 2012

31

Obionin B: an o-pyranonaphthoquinone decaketide from an unidentified fungus (MSX 63619) from the order Pleosporales

Sloan Ayers, Tyler N. Graf, Audrey F. Adcock, David J. Kroll, Qi Shen, Steven M. Swanson, Mansukh C. Wani, Blaise A. Darveaux, Cedric J. Pearce, Nicholas H. Oberlies

Journal:

Tetrahedron Letters

Year:

2011

Language:

english

File:

PDF, 264 KB

english, 2011

32

Thielavin B methyl ester: a cytotoxic benzoate trimer from an unidentified fungus (MSX 55526) from the Order Sordariales

Sloan Ayers, Brandie M. Ehrmann, Audrey F. Adcock, David J. Kroll, Mansukh C. Wani, Cedric J. Pearce, Nicholas H. Oberlies

Journal:

Tetrahedron Letters

Year:

2011

Language:

english

File:

PDF, 366 KB

english, 2011

33

Pre-clinical evaluation of SN-38 and novel camptothecin analogs against human chronic B-cell lymphocytic leukemia lymphocytes

Darrel P Cohen, David J Adams, James L Flowers, Monroe E Wall, Mansukh C Wani, G Manikumar, O.Michael Colvin, Robert Silber

Journal:

Leukemia Research

Year:

1999

Language:

english

File:

PDF, 209 KB

english, 1999

34

Correction to Cyclodepsipeptides, Sesquiterpenoids, and Other Cytotoxic Metabolites from the Filamentous Fungus Trichothecium sp. (MSX 51320)

Sy-Cordero, Arlene A., Graf, Tyler N., Adcock, Audrey F., Kroll, David J., Shen, Qi, Swanson, Steven M., Wani, Mansukh C., Pearce, Cedric J., Oberlies, Nicholas H.

Journal:

Journal of Natural Products

Year:

2012

Language:

english

File:

PDF, 113 KB

english, 2012

35

Gummiferol, a Cytotoxic Polyacetylene from the Leaves of Adenia gummifera

Fullas, Fekadu, Brown, Daniel M., Wani, Mansukh C., Wall, Monroe R., Chagwedera, Tangai E., Farnsworth, Norman R., Pezzuto, John M., Kinghorn, A. Douglas

Journal:

Journal of Natural Products

Year:

1995

Language:

english

File:

PDF, 264 KB

english, 1995

36

Resorcylic Acid Lactones with Cytotoxic and NF-κB Inhibitory Activities and Their Structure–Activity Relationships

Ayers, Sloan, Graf, Tyler N., Adcock, Audrey F., Kroll, David J., Matthew, Susan, Carcache de Blanco, Esperanza J., Shen, Qi, Swanson, Steven M., Wani, Mansukh C., Pearce, Cedric J.

Journal:

Journal of Natural Products

Year:

2011

Language:

english

File:

PDF, 1.43 MB

english, 2011

37

Cytotoxic Prenylated Xanthones and the Unusual Compounds Anthraquinobenzophenones from Cratoxylum sumatranum1

Seo, Eun-Kyoung, Kim, Nam-Cheol, Wani, Mansukh C., Wall, Monroe E., Navarro, Hernán A., Burgess, Jason P., Kawanishi, Kazuko, Kardono, Leonardus B. S., Riswan, Soedarsono, Rose, William C.

Journal:

Journal of Natural Products

Year:

2002

Language:

english

File:

PDF, 74 KB

english, 2002

38

Human DNA Topoisomerase I: Quantitative Analysis of the Effects of Camptothecin Analogs and the Benzophenanthridine Alkaloids Nitidine and 6-Ethoxydihydronitidine on DNA Topoisomerase I-Induced DNA Strand Breakage

Joseph A. Holden, Monroe E. Wall, Mansukh C. Wani, Govindarajan Manikumar

Journal:

Archives of Biochemistry and Biophysics

Year:

1999

Language:

english

File:

PDF, 271 KB

english, 1999

39

Antitrypanosomal activity of camptothecin analogs: Structure-activity correlations

Annette L. Bodley, Mansukh C. Wani, Monroe E. Wall, Theresa A. Shapiro

Journal:

Biochemical Pharmacology

Year:

1995

Language:

english

File:

PDF, 697 KB

english, 1995

40

Plant antitumor agents. 30. Synthesis and structure activity of novel camptothecin analogs

Wall, Monroe E., Wani, Mansukh C., Nicholas, Allan W., Manikumar, Govindarajan, Tele, Chhagan, Moore, Linda, Truesdale, Anne, Leitner, Peter, Besterman, Jeffrey M.

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 1.74 MB

english, 1993

41

Plant antitumor agents. 18. Synthesis and biological activity of camptothecin analogs

Wani, Mansukh C., Ronman, Peter E., Lindley, James T., Wall, Monroe E.

Journal:

Journal of Medicinal Chemistry

Year:

1980

Language:

english

File:

PDF, 1.03 MB

english, 1980

42

Cyclodepsipeptides, Sesquiterpenoids, and Other Cytotoxic Metabolites from the Filamentous Fungus Trichothecium sp. (MSX 51320)

Sy-Cordero, Arlene A., Graf, Tyler N., Adcock, Audrey F., Kroll, David J., Shen, Qi, Swanson, Steven M., Wani, Mansukh C., Pearce, Cedric J., Oberlies, Nicholas H.

Journal:

Journal of Natural Products

Year:

2011

Language:

english

File:

PDF, 3.12 MB

english, 2011

43

Reversal of activity profile in analogs of the antiprogestin RU 486: Effect of a 16α-substituent on progestational (agonist) activity

C. Edgar Cook, Mansukh C. Wani, Yue-Wei Lee, Patricia A. Fail, Vladimir Petrow

Journal:

Year:

1993

Language:

english

File:

PDF, 441 KB

english, 1993

44

Cytotoxic epipolythiodioxopiperazine alkaloids from filamentous fungi of the Bionectriaceae

Figueroa, Mario, Graf, Tyler N, Ayers, Sloan, Adcock, Audrey F, Kroll, David J, Yang, Jilai, Swanson, Steven M, Munoz-Acuna, Ulyana, Carcache de Blanco, Esperanza J, Agrawal, Rajesh, Wani, Mansukh C,

Journal:

The Journal of Antibiotics

Year:

2012

Language:

english

File:

PDF, 1.16 MB

english, 2012

45

Benzoquinones and Terphenyl Compounds As Phosphodiesterase-4B Inhibitors from a Fungus of the Order Chaetothyriales (MSX 47445)

El-Elimat, Tamam, Figueroa, Mario, Raja, Huzefa A., Graf, Tyler N., Adcock, Audrey F., Kroll, David J., Day, Cynthia S., Wani, Mansukh C., Pearce, Cedric J., Oberlies, Nicholas H.

Journal:

Journal of Natural Products

Year:

2013

Language:

english

File:

PDF, 2.26 MB

english, 2013

46

Plant antitumor agents. 29. Synthesis and biological activity of ring D and ring E modified analogs of camptothecin

Nicholas, Allan W., Wani, Mansukh C., Manikumar, Govindarajan, Wall, Monroe E., Kohn, Kurt W., Pommier, Yves

Journal:

Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 1.02 MB

english, 1990

47

Plant antitumor agents. 25. Total synthesis and antileukemic activity of ring A substituted camptothecin analogs. Structure-activity correlations

Wani, Mansukh C., Nicholas, Allan W., Manikumar, Govindarajan, Wall, Monroe E.

Journal:

Journal of Medicinal Chemistry

Year:

1987

Language:

english

File:

PDF, 944 KB

english, 1987

48

New Compounds with DNA Strand-Scission Activity from the Combined Leaf and Stem of Uvaria hamiltonii

Huang, Li, Wall, Monroe E., Wani, Mansukh C., Navarro, Hernán, Santisuk, Thawatchai, Reutrakul, Vichai, Seo, Eun-Kyoung, Farnsworth, Norman R., Kinghorn, A. Douglas

Journal:

Journal of Natural Products

Year:

1998

Language:

english

File:

PDF, 88 KB

english, 1998

49

Isolation and Structure Identification of an Active DNA Strand-Scission Agent, (+)-3,4-di-hydroxy-8,9-Methylenedioxypterocarpan

Chaudhuri, Swapan K., Huang, Li, Fullas, Fekadu, Brown, Daniel M., Wani, Mansukh C., Wall, Monroe E., Tucker, John C., Beecher, Christopher W. W., Kinghorn, A. Douglas

Journal:

Journal of Natural Products

Year:

1995

Language:

english

File:

PDF, 327 KB

english, 1995

50

Peptaibols, Tetramic Acid Derivatives, Isocoumarins, and Sesquiterpenes from a Bionectria sp. (MSX 47401)

Figueroa, Mario, Raja, Huzefa, Falkinham, Joseph O., Adcock, Audrey F., Kroll, David J., Wani, Mansukh C., Pearce, Cedric J., Oberlies, Nicholas H.

Journal:

Journal of Natural Products

Year:

2013

Language:

english

File:

PDF, 3.02 MB

english, 2013